Sleep disorders, particularly insomnia, have become increasingly prevalent in modern societies due to stress, lifestyle changes, and health conditions. Among the medications used to treat insomnia, zopiclone and its active isomer eszopiclone are widely prescribed worldwide. These non-benzodiazepine hypnotics belong to the “Z-drug” class and are known for their relatively favorable safety profile and effectiveness in inducing and maintaining sleep. India, being one of the largest pharmaceutical producers in the world, offers a wide range of affordable zopiclone and eszopiclone brands that are distributed both domestically and internationally. This article explores some of the most popular Indian brands of these medications, their characteristics, and what makes them sought after in global markets.
Understanding Zopiclone and Eszopiclone
Zopiclone
Zopiclone is a short-acting sedative-hypnotic used primarily for the short-term management of insomnia. It helps people fall asleep faster, reduces nighttime awakenings, and improves sleep duration and quality.
Eszopiclone
Eszopiclone is the S-enantiomer of zopiclone and is considered more potent and better tolerated in some patients. It is marketed in certain countries under the trade name Lunesta, among others, and is often chosen for longer-term use due to its slightly improved side-effect profile.
Both drugs act by binding to GABA-A receptors in the brain, enhancing the inhibitory effects of GABA, and promoting sleep.
Major Indian Brands of Zopiclone and Eszopiclone
1. ZOP 7.5
One of the most recognizable zopiclone brands in India is ZOP 7.5, manufactured by HAB Pharmaceuticals. It contains 7.5 mg of zopiclone per tablet, which is the typical starting dose for adults with insomnia.
ZOP is widely exported and has become a popular choice in markets where generic sleeping pills are sought for affordability and effectiveness. Its simple formulation and consistent quality have contributed to its popularity.
2. Zopisign
Zopisign is another prominent brand, produced by HAB Pharmaceuticals. It comes in 7.5 mg and 10 mg strengths and is known for its reliable effects and affordability. Zopisign is commonly used in both domestic and international markets by patients who need short-term relief from insomnia.
The brand’s growing recognition is also due to its easy availability through online pharmacies and export-oriented companies.
3. Hypnite
Hypnite, manufactured by Consern Pharma, is a trusted name among Indian zopiclone brands. Available in 3.75 mg and 7.5 mg doses, Hypnite is often chosen for its consistent quality and competitive pricing. Its low-dose options make it suitable for elderly patients and those who require minimal effective doses to avoid side effects.
Hypnite has carved out a place in the market as a reliable, patient-friendly choice.
4. Eszop
For eszopiclone, Eszop is one of the emerging Indian brands. Eszop provides the S-enantiomer formulation of zopiclone, which is believed to offer similar efficacy at lower doses and fewer metallic aftertastes — a common complaint with racemic zopiclone.
Eszop is marketed in strengths like 2 mg and 3 mg, which aligns with international dosing standards for eszopiclone.
5. Other Notable Brands
Several other Indian pharmaceutical companies also produce zopiclone and eszopiclone under various brand names. Some of these include:
- Zopicon — another HAB Pharmaceuticals brand, similar to ZOP and Zopisign.
- Eszopira — eszopiclone brand produced for patients who prefer the single-isomer formulation.
- Zopidra — marketed as an affordable alternative to better-known brands.
- Zopinap — a lesser-known but increasingly distributed generic zopiclone.
These brands offer different packaging, price points, and formulations to cater to a wide range of patients.
Why Indian Brands Are Popular Globally
Affordable Pricing
One of the biggest advantages of Indian zopiclone and eszopiclone brands is their cost-effectiveness. Due to India’s robust generic pharmaceutical industry and lower production costs, Indian brands are much cheaper than branded versions sold in Western countries.
Quality Standards
Many zopiclone vendors from India, such as HAB and Consern Pharma, comply with WHO-GMP, USFDA, and EU-GMP guidelines, ensuring that the medicines meet international quality and safety standards.
Wide Availability
Indian brands are widely available through both physical and online pharmacies. They are also exported in large volumes to countries in Asia, Africa, and parts of Europe, where demand for affordable sleep aids is high.
Considerations for Use
While zopiclone and eszopiclone are effective sleep aids, they should be used responsibly:
- They are recommended only for short-term use, typically 2–4 weeks, to avoid dependence and tolerance.
- They should be taken only under medical supervision, especially in elderly patients and those with a history of substance abuse.
- Side effects can include metallic taste, dizziness, and in rare cases, parasomnias (sleepwalking, etc.).
Patients are advised to consult a doctor and follow dosing instructions carefully.
Conclusion
Indian pharmaceutical companies have established themselves as leading suppliers of affordable and reliable zopiclone and eszopiclone brands. ZOP 7.5, Zopisign, Hypnite, Eszop, and others have become household names not just in India but also in international markets.
These brands continue to grow in popularity due to their competitive pricing, high-quality manufacturing, and effectiveness in treating insomnia. Nevertheless, it is crucial to remember that these medications should always be used under professional medical guidance to minimize risks and ensure safe use.
For patients struggling with insomnia, consulting a healthcare provider and exploring the right treatment — whether it’s zopiclone, eszopiclone, or behavioral therapies — is the best approach to achieving better sleep and overall well-being.